Excellent chemical plant bulk supply Tanshinone IIA 568-72-9 We provide high quality Tanshinone IIA (CAS 568-72-9), at a very affordable prices to our customers.

1.What is the Tanshinone IIA ?

Tanshinone IIA (TSA) is a major lipophilic component of extracts from the root of S. miltiorrhiza, used widely in Chinese herbal medicine. It has anti-inflammatory activity, inhibiting production of TNF-α, IL-1β, IL-6, NO, INFγ, and expression of iNOS, and IL-12. It blocks human aortic smooth muscle cell migration, inhibits MMP-9 activity, and interferes with PI3K/Akt and ERK1/2 signaling pathways. It is cytotoxic to various cancer cells including A549 lung cancer cells and leukemia cells.Reduction of TSA by NAD(P)H:quinone oxidoreductase (NQO1) generates an unstable intermediate resulting in reactive oxygenase species-mediated apoptotic cell death.

antineoplastic, bone resorption inhibitor, antiproliferative, apoptosis inducer

2.What is the CAS number for Tanshinone IIA ?

The CAS number of Tanshinone IIA is 568-72-9.

More information of Tanshinone IIA 568-72-9 are:

3.What is the molecular formula of Tanshinone IIA ?

The chemical formula of?Tanshinone IIA is C19H18O3 which containing 19 Carbon atoms,18 Hydrogen atoms and 3 Oxygen atoms,and the molecular weight, and the molecular weight of Tanshinone IIA is 294.35

4.What is Tanshinone IIA(568-72-9)used for?

Tanshinone IIA (TSA) is a major lipophilic component of extracts from the root of S. miltiorrhiza, used widely in Chinese herbal medicine. It has anti-inflammatory activity, inhibiting production of TNF-α, IL-1β, IL-6, NO, INFγ, and expression of iNOS, and IL-12. It blocks human aortic smooth muscle cell migration, inhibits MMP-9 activity, and interferes with PI3K/Akt and ERK1/2 signaling pathways. It is cytotoxic to various cancer cells including A549 lung cancer cells and leukemia cells.Reduction of TSA by NAD(P)H:quinone oxidoreductase (NQO1) generates an unstable intermediate resulting in reactive oxygenase species-mediated apoptotic cell death.

InChI:InChI=1/C19H20O3/c1-10-9-22-18-12-6-7-13-11(5-4-8-19(13,2)3)15(12)17(21)16(20)14(10)18/h6-7,10H,4-5,8-9H2,1-3H3

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5.Excellent chemical plant bulk supply Tanshinone IIA 568-72-9

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