What is the (Z)-Akuammidine?

(Z)-Akuammidine is , while it's Molecular Formula is C 21 H 24 N 2 O 3 . Used in Pharmaceutical Industry: (Z)-Akuammidine is used as an antiplasmodial agent for its ability to inhibit the growth of Plasmodium falciparum, the parasite responsible for causing malaria. Its effectiveness in combating this deadly disease highlights its potential as a therapeutic agent in the fight against malaria. (Z)-Akuammidine is also used as an antinociceptive agent due to its demonstrated ability to alleviate pain. This property suggests its potential use as an analgesic, offering a natural alternative for pain management. Further research is necessary to fully understand the pharmacological activities and explore additional therapeutic applications of (Z)-Akuammidine, including its potential synergistic effects when combined with other medications or its use in drug delivery systems to enhance bioavailability and therapeutic outcomes.

What is the CAS number for (Z)-Akuammidine?

The CAS number of (Z)-Akuammidine is 113973-31-2.

What is (Z)-Akuammidine (113973-31-2) used for?

(Z)-Akuammidine, a naturally occurring alkaloid, is derived from the stem bark extracts of the plant Picralima nitida. It has garnered attention for its potential medicinal properties, particularly its antiplasmodial and antinociceptive effects. (Z)-Akuammidine's unique structure and bioactivity make it a subject of interest for pharmaceutical research and development.

What is the (Z)-Akuammidine?

(Z)-Akuammidine is , while it's Molecular Formula is C 21 H 24 N 2 O 3 . Used in Pharmaceutical Industry: (Z)-Akuammidine is used as an antiplasmodial agent for its ability to inhibit the growth of Plasmodium falciparum, the parasite responsible for causing malaria. Its effectiveness in combating this deadly disease highlights its potential as a therapeutic agent in the fight against malaria. (Z)-Akuammidine is also used as an antinociceptive agent due to its demonstrated ability to alleviate pain. This property suggests its potential use as an analgesic, offering a natural alternative for pain management. Further research is necessary to fully understand the pharmacological activities and explore additional therapeutic applications of (Z)-Akuammidine, including its potential synergistic effects when combined with other medications or its use in drug delivery systems to enhance bioavailability and therapeutic outcomes.

What is the CAS number for (Z)-Akuammidine?

The CAS number of (Z)-Akuammidine is 113973-31-2.

What is (Z)-Akuammidine (113973-31-2) used for?

(Z)-Akuammidine, a naturally occurring alkaloid, is derived from the stem bark extracts of the plant Picralima nitida. It has garnered attention for its potential medicinal properties, particularly its antiplasmodial and antinociceptive effects. (Z)-Akuammidine's unique structure and bioactivity make it a subject of interest for pharmaceutical research and development.

Bulk supply high purity (Z)-Akuammidine 113973-31-2, Paid sample available

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Product

(Z)-Akuammidine

CAS No.: 113973-31-2
Purity: 99%

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Bulk supply high purity (Z)-Akuammidine 113973-31-2, Paid sample available

Molecular Formula: C₂₁H₂₄N₂O₃
Molecular Weight: 352.433
Melting Point: 240-242 °C(Solv: acetone (67-64-1))
Boiling Point: 513.0±50.0 °C(Predicted)
PKA: 14.79±0.10(Predicted)
PSA： 65.56000
Density: 1.34±0.1 g/cm3(Predicted)
LogP: 2.50510

113973-31-2 Relevant articles

CHARACTERISTICS OF VELLOSIMINE REDUCTASE, A SPECIFIC ENZYME INVOLVED IN THE BIOSYNTHESIS OF THE RAUWOLFIA ALKALOID SARPAGINE

Pfitzner, Artur,Krausch, Brigitte,Stoeckigt, Joachim

, p. 1691 - 1700 (2007/10/02)

A plant enzyme - vellosimine reductase -...

113973-31-2 Process route

: 639-36-1,6872-44-2,113973-31-2
17-hydroxy-sarpagane-16-carboxylic acid methyl ester

Conditions

Conditions	Yield
Aldehyd (II), NaBH4;

: 2520-44-7,92218-35-4
Polyneuridine aldehyde

: 639-36-1,6872-44-2,113973-31-2
akuammidine

Conditions

Conditions	Yield
With NADPH; Vellosimine reductase;

113973-31-2 Upstream products

2520-44-7
Polyneuridine aldehyde

113973-31-2 Downstream products

2520-44-7
(2S,6S,13S)-3-Eth-(E)-ylidene-13-formyl-1,3,4,7,12,12b-hexahydro-2H,6H-2,6-methano-indolo[2,3-a]quinolizine-13-carboxylic acid methyl ester
6874-98-2
vellosimine